A Florida mother vanishes into the night after celebrating her daughter's first birthday. In their search to find her, the police seek answers from the father of her child.

When a young woman vanishes, detectives zero in on her controlling estranged husband--whose story continually changes in the interrogation room.

After an 80-year-old woman vanishes, local police and the FBI team up in the pursuit of a suspected serial killer.

After police respond to an apparent suicide, the case takes an unexpected turn when investigators cannot find a gun near the body.

In a story that gripped the nation, three Cleveland women are rescued ten years after vanishing from the city's streets. Now, authorities must confront the man at heart of this notorious crime to unravel the sinister details surrounding the abductions.

At the scene of a chilling triple murder in Northern Maine, detectives recover DNA evidence that suggests an out-of-town visitor may be behind the brutal crime. Inside the interrogation room, will the suspect cave to the pressure and confess?

After a deceased baby is found hidden in a cardboard box, investigators question the mother and her estranged husband to figure out who is responsible for this horrific crime.

Ten years after a young mother allegedly abandoned her family, her mother-in-law reveals a shocking secret: she believes both of her daughter-in-law's lovers murdered her.

Detectives investigate two sisters after a witness presents evidence that an elderly man's death was anything but natural.

When an otherwise healthy young woman is admitted to the hospital with sudden organ failure, an anonymous tip leads authorities to investigate a pattern of unexplained deaths in her family and a shocking prime suspect.

When an elderly woman is brutally assaulted and left fighting for her life, investigators quickly try to find the man responsible.

Six years after a drive-by shooting, detectives uncover a violent feud that may have led to the gruesome murder.

After decades on the run, a serial killer faces tough questions in the interrogation room and a woman is found dead in the middle of the road.

After a successful businessman is brutally strangled, investigators become suspicious of his widow and her secret friend.

After 22 years, a local news story reignites a decades-old cold case, leading investigators to question a close-knit circle of friends who they believe are hiding the truth.

A series of random nighttime shootings has the city of Phoenix on edge as police try to end the reign of terror and interrogate two suspects.

After the dismembered remains of a missing woman are found in a freezer, investigators uncover a love triangle and a murderous conspiracy to conceal the truth.

After a man and a woman are found shot on the side of the highway, investigators struggle to find clues to catch the killer.

When a 70-year-old grandmother passes away suspiciously on a road trip, investigators uncover a sinister murder plot while searching for her remains.

When a 25-year-old college student vanishes on Christmas Eve, investigators must piece together the details of a first date gone tragically wrong.

The search for a missing priest leads detectives on a multi-state manhunt for a suspect who may be the only person with the answers to his whereabouts.